India vaccine trials likely in Oct.

India vaccine trials likely in Oct.

Preclinical studies have to be completed before human trials, says official

29/05/2020, SPECIAL CORRESPONDENT,NEW DELHI

In the making: Six promising vaccine candidates are being developed from India. AP

A novel coronavirus vaccine being developed in India will likely begin to be tested in people in October, K. VijayRaghavan, Principal Scientific Adviser to the government, said at a press briefing on Thursday.

“A group is working on a vaccine on a flu backbone. Preclinical studies are likely to be completed by October after which it is likely to move on to human trials,” he said, without disclosing the identity of the company or group.

Another vaccine group had developed a promising protein that would be ready to be tested by next February. India was looking at both indigenous as well as foreign collaborations, he added.

NITI Aayog member V.K. Paul said six promising vaccine were candidates being developed from India.

The Hyderabad-based Bharat Biotech announced in April that it was part of an international collaboration of virologists at the University of Wisconsin-Madison and U.S. vaccine company FluGen to develop ‘CoroFlu,’ a nasally administered inoculant.

In response to a question by The Hindu whether the tests of the Serum Institute-Oxford University vaccine candidate that showed the vaccine failed to check virus spread in monkeys but reduced severe disease were promising, Mr. VijayRaghavan said it was a matter of interpreting the “glass as half full or half empty”. The scale of the pandemic was such that it did not matter which company made a vaccine first, and there was enough room for promising vaccine candidates that would take a while to develop. Moreover, it was possible for vaccines to show limited efficacy in primates but be more protective in people.

“It’s still early days,” he added.

Dr. Paul, who is heading an empowered group on medical equipment and management plan to tackle the outbreak, said the results of a major sero-prevalence survey by the Indian Council of Medical Research (ICMR) in 69 districts to estimate the level of infection in several districts were expected next week.