Finds A Pilot Study By ICMR
Sushmi.Dey@timesgroup.com
New Delhi:29.08.2021
A single-dose of Bharat Biotech’s Covaxin in people who had been infected with Covid-19 previously generates antibody response similar to that provided by two doses of the vaccine in those without any history of the infection, shows a pilot study by the Indian Council of Medical Research (ICMR).
The findings are based on preliminary data and need to be confirmed with large-sized cohort studies, it said.
The study assumes significance because if ICMR can validate the initial findings through a large-scale study, it can be instrumental in expediting the coverage.
“This study offers evidence in support of public health-oriented and immunologically sustained vaccine strategies. If our preliminary findings are confirmed in large population studies, a single dose of BBV152 vaccine may be recommended to previously confirmed SARS-CoV-2 infected individuals so that the naïve individuals could attain the larger benefit of a limited vaccine supply,” says the short paper with the findings of the study published in the Indian Journal of Medical Research.
However, the authors underlined that both vaccine doses would be ideal even for previously infected individuals in the long run due to the occurrence of variants of concern.
Bharat Biotech’s Covaxin is currently administered in a two-dose regimen with a gap of four to six weeks.
The ICMR study was undertaken to examine SARSCoV-2–specific antibody responses after day zero (baseline, before vaccination), Day 28 (month 1) and Day 56 post-first dose (month 2) of Covaxin in a group of healthcare professionals as well as front-line workers.
The antibody response of individuals with confirmed pre-vaccination SARSCoV-2 infection was compared with those individuals without prior evidence of infection.
A woman takes a selfie as a health worker administers a vaccine for Covid-19 at District Govt Women’s Hospital in Varanasi, on Saturday
Fully vaxxed desis can now fly to SL
Sri Lanka announced on Saturday that it was reopening its borders for India as it said fully vaccinated Indian travellers will only require a negative RT-PCR test, done 72 hours prior to arrival, and an on-arrival test at a certified hotel. Sri Lankan Airlines will operate four weekly flights to Chennai, three to Mumbai, and one to Bengaluru under its new schedule, and is likley to introduce “significant frequency enhancements”. TNN
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